Go straight to the text The care word map Words for an online care conversation Browse the word map Find your bearings Care word map The word map Telehealth Tirzepatide A care conversation Specialist Licence Assessment Prescription The medicine words Approval Compounding Shortage Trial evidence Unwanted effects Misleading offers Payment and questions Self-pay Coverage Prior approval Care questions Trial evidence # Study results describe groups of people, not your own result. A trial is a study of a group of people. To understand its results, look at who took part, their care, and what treatments were compared. Jump to a section What a weight study found What happened after treatment changed Read the result with its limits Read the source pages ## Put study results beside their limits ### What a weight study found SURMOUNT-1 enrolled no one with diabetes; its adults had obesity, or they were overweight with an associated health problem. At 72 weeks, average weight loss across the tirzepatide groups ranged from 15.0% to 20.9%, compared with 3.1% in the dummy-shot group. The maker funded the study, and participants received lifestyle counselling along with regular visits. A group average does not give you a personal target. Ask how the study group compares with your own health and care setting. ### What happened after treatment changed In SURMOUNT-4, participants first had 36 weeks of tirzepatide before being assigned to continue it or switch to a dummy shot. During the next 52 weeks, the people switched to dummy shots gained an average of 14.0% of their weight at week 36. Those who kept taking tirzepatide lost another 5.5%, also measured from their weight at week 36. At the end, the groups still weighed less than before starting: 9.9% less after switching, and 25.3% less after continuing tirzepatide. Ask how the clinician plans to discuss stopping, changing, or continuing care. Keep that question alongside the cost of ongoing visits. ### Read the result with its limits Ask how the study’s people and care compare with your own circumstances. Who took part? What did the comparison group receive? What can this study leave unanswered for me? ## Read the source pages Weight-study paper For the weight change, comparison group, and trial setting. Treatment-change paper For the groups that continued or changed treatment. Read about unwanted effects This care-word guide offers reading, runs no clinic, and sells no medicine. Find a word Carry a question Back to this word